Are soluble ST2 levels influenced by vitamin D and/or the seasons?
نویسندگان
چکیده
منابع مشابه
Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33
In our cohort of patients with severe asthma, the majority receiving very high doses of inhaled or systemic corticosteroids, a blood eosinophil count of greater than 0.45 3 10 cells/L can correctly predict sputum eosinophilia in 9 of 10 cases. We have included only patients with severe asthma in our study, and therefore we believe our results are important because these are the patients who wil...
متن کاملMaternal Vitamin D Status in Preeclampsia: Seasonal Changes Are Not Influenced by Placental Gene Expression of Vitamin D Metabolizing Enzymes
UNLABELLED Preeclampsia, a hypertensive disorder in pregnancy develops in 2-8% of pregnancies worldwide. Winter season and vitamin D deficiency have been associated with its onset. OBJECTIVE To investigate the influence of season on maternal vitamin D status and placental vitamin D metabolism. METHODS 25-OH vitamin D and 1,25-(OH)2 vitamin D were measured in maternal serum obtained during t...
متن کاملVitamin D in MS: a vitamin for 4 seasons.
OBJECTIVE: There is increasing evidence that vitamin D can be protective against the development of multiple sclerosis (MS), but it may also be beneficial for the clinical course of the disease. Our objective was to prospectively investigate if 25-hydroxy-vitamin D (25OH-D) levels are associated with exacerbation risk in MS in a study with frequent serum measurements. METHODS: This was a prospe...
متن کاملSoluble ST2 Levels Are Associated with Bleeding in Patients with Severe Leptospirosis
BACKGROUND Severe leptospirosis features bleeding and multi-organ failure, leading to shock and death. Currently it is assumed that both exaggerated inflammation and immune suppression contribute to mortality in sepsis. Indeed, several proinflammatory cytokines are reported to be induced during leptospirosis. Toll-like receptors, which play an important role in the initiation of an innate immun...
متن کاملTesting vitamin D levels.
Evidence • A systematic review1 on 25-hydroxyvitamin D (25[OH] D) suggests levels greater than 75 nmol/L “are not consistently associated with increased benefit”; greater than 50 nmol/L are “practically sufficient for all persons”; between 30 and 50 nmol/L “places some, but not all, persons at risk for inadequacy”; and less than 30 nmol/L puts one “at risk relative to bone health.” • No RCTs in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrine Connections
سال: 2019
ISSN: 2049-3614
DOI: 10.1530/ec-19-0090